The gap
Most probiotics die before they arrive
Conventional strains are fragile — they need refrigeration to stay alive on the shelf and still have to survive stomach acid afterward. Two chances to fail before doing anything.
of the immune system resides in the gut, where protein quality and beneficial bacteria both play a role.
published studies on DE111® Bacillus subtilis, examining its safety and activity in the digestive tract.
Why this formula
A probiotic built to survive the trip
Spore-forming, shelf stable, and still alive when it matters.
Bacillus subtilis is a spore-forming bacterium, which means it travels in a dormant protective shell and germinates once it reaches the intestine. That single property solves both problems conventional probiotics have: it doesn't need refrigeration to stay viable, and it isn't destroyed by stomach acid on the way down. It's also the reason a probiotic can work in a gummy — a refrigerated Lactobacillus never could.
DE111® is the specific strain, developed by Deerland and examined across more than thirty published studies. At 5 billion CFU per serving, it supports a balanced gut microbiome, normal digestion, and the nutrient absorption that depends on both. Two strawberry gummies, no capsules, nothing to keep cold.
What it supports
What one serving covers
The support this formula is built to give.
Survives the Trip
The spore form travels protected through stomach acid and germinates in the intestine, where a probiotic is supposed to work.
Microbiome Balance
DE111® supports a balanced gut microbiota, helping beneficial bacteria establish and hold their place.
Digestive Support
Supports comfortable digestion and the nutrient absorption that depends on a healthy gut.
Immune Support
Supports your body's everyday immune function.
What's inside
The ingredients doing the work
DE111® (Bacillus subtilis)
5 billion CFUA spore-forming probiotic strain that survives stomach acid and germinates in the intestine to support microbiome balance.
More on this ingredient
DE111® is a registered trademark of Deerland Probiotics & Enzymes, examined in over thirty published studies. Because it's spore-forming, it stays viable at room temperature and doesn't require refrigeration — unlike the Lactobacillus and Bifidobacterium strains used in most probiotics.
- The only active in the formula
- Shelf stable, no cold chain required
- Vegan, non-GMO
How to take it
How to take it
The whole routine, start to finish.
Two gummies
Two gummies is the full serving. No water needed.
DailyMorning, empty stomach
First thing in the morning, before food, supports the fullest absorption.
MorningEvery day
A microbiome shifts through consistent daily input, not occasional large doses.
DailyPro tips
- Morning, before breakfast, is the best window.
- Two gummies is the serving; more doesn't speed anything up.
- No refrigeration needed — store at room temperature.
- Kids take these without a fight; check the age with your pediatrician.
- Consistency matters more than timing. Every day beats a big dose sometimes.
The honest comparison
Not all of them are the same
Where the differences actually sit.
| Feature | nanoPROBIOTIC | Refrigerated probiotic | Standard probiotic gummy |
|---|---|---|---|
| Spore-forming, survives stomach acid | ✓ Yes | ✕ No | ✕ No |
| Shelf stable, no refrigeration | ✓ Yes | ✕ No | ✓ Yes |
| Single named, trademarked strain | ✓ Yes | — Varies | ✕ No |
| 30+ published studies on the strain | ✓ Yes | — Varies | ✕ No |
| 5 billion CFU guaranteed per serving | ✓ Yes | ✓ Yes | — Varies |
| Format kids will actually take | ✓ Yes | ✕ No | ✓ Yes |
Comparison reflects category averages for standalone products at comparable dosages — not any specific brand.
How everything here works
You are what you absorb
You can take the best formula in the world and still get very little from it. Absorption is the part nobody talks about, because the ingredient that solves it costs money.
Every product we make is built around getting nutrients into you rather than just into the tub — enzymes where they help, cold processing that doesn't cook nutrients off, and forms chosen for uptake over shelf price.
Where we started
Recommended in practice, not in ads
BioPharma Scientific formulas were developed for and distributed through doctors, chiropractors and naturopaths for years before anything was sold direct.
Many still stock them today. That channel is why the formulas are built around absorption instead of shelf price.
Questions
Not finding it? We answer within one business day.
A specific strain of Bacillus subtilis developed by Deerland Probiotics & Enzymes and examined in more than thirty published studies. Naming the strain matters — probiotic activity is strain-specific, so “contains Bacillus subtilis” tells you much less than a trademarked, studied strain does.
The bacteria travel in a dormant protective shell rather than in an active, fragile state. That shell survives stomach acid, and the organism germinates once it reaches the intestine. Most probiotic strains have no such protection, which is why so much of a conventional dose never arrives intact.
No. The spore form stays viable at room temperature, which is what makes a shelf-stable probiotic gummy possible in the first place. Store it in a cool, dry place.
The strawberry gummy format is the easiest way to get a probiotic into a child without a negotiation. Check the appropriate serving with your pediatrician before starting.
First thing in the morning on an empty stomach works well, though the spore form means it isn't fragile about timing. Daily consistency matters more — a microbiome shifts gradually.
Love it, or get your money back
Try it for thirty days. If it isn't for you, contact us for a full refund — opened tub and all.
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*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Consult your physician or healthcare provider before taking any of our products. Individual results may vary.